Description

n-(Piperidin-4-Yl)Pyridine-2-Sulfonamidedihydrochloride is a high-purity sulfonamide derivative, primarily utilized as a sophisticated pharmaceutical intermediate and a key building block in medicinal chemistry research. Its molecular structure makes it a valuable scaffold for the development of novel therapeutic agents, particularly in targeting specific enzymes and receptors. This compound is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical synthesis sectors seeking to create new drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Protease Inhibitor Development: Serves as a precursor or key fragment in the design of inhibitors for various protease enzymes.
• Kinase Inhibitor Synthesis: Employed in the construction of molecules designed to modulate kinase activity, relevant in oncology and inflammatory diseases.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke organic synthesis projects requiring high-purity, complex heterocyclic compounds.

Basic Information

Product Name	n-(Piperidin-4-Yl)Pyridine-2-Sulfonamidedihydrochloride
CAS No.	1233955-74-2
Molecular Formula	C10H15N3O2S • 2HCl
Molecular Weight	338.23 g/mol (free base: 225.31 g/mol)
Synonyms	2-Pyridinesulfonamide, N-(4-piperidinyl)-, dihydrochloride; 4-(2-Pyridylsulfonamido)piperidine Dihydrochloride; N-(Piperidin-4-yl)pyridine-2-sulfonamide Dihydrochloride; 1233955-74-2; 4-(Pyridine-2-sulfonylamino)piperidine Dihydrochloride; Piperidine-4-yl-pyridine-2-sulfonamide Dihydrochloride
EINECS	Contact for details

Quality Control

Our n-(Piperidin-4-Yl)Pyridine-2-Sulfonamidedihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with lot-specific data are provided to guarantee traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.