Description

tert-Butyl 4-Pivalamidopiperidine-1-Carboxylate is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of novel active pharmaceutical ingredients (APIs) and other biologically relevant compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Peptidomimetic Scaffold: Used to create constrained peptide analogs and protease inhibitors due to its rigid piperidine core and amide functionality.
• Ligand and Receptor Probe Development: Employed in the design and synthesis of molecular probes for studying biological targets and signal transduction pathways.
• Building Block for Chemical Libraries: Integral for combinatorial chemistry and high-throughput screening libraries in drug discovery programs.
• Agrochemical Research: Serves as a precursor in the development of new crop protection agents and herbicides.
• Academic and Contract Research: Used in university and CRO (Contract Research Organization) settings for methodological development and novel compound synthesis.

Basic Information

Product Name	tert-Butyl 4-Pivalamidopiperidine-1-Carboxylate
CAS No.	1233955-60-6
Molecular Formula	C15H28N2O3
Molecular Weight	284.40 g/mol
Synonyms	1-Boc-4-(pivalamido)piperidine; 4-(2,2-Dimethylpropanamido)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(pivalamido)piperidine-1-carboxylate; 4-(Pivalamido)-1-Boc-piperidine; 1-(tert-Butoxycarbonyl)-4-pivalamidopiperidine; N-(1-Boc-4-piperidinyl)pivalamide; Boc-4-Pivalamido-piperidine; 4-Pivalamidopiperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Pivalamidopiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.