Description

tert-Butyl 4-(3-Nitrobenzylamino)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core and nitrobenzylamino functional group. This compound is of significant value for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric research. It is primarily needed by R&D laboratories, custom synthesis providers, and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Custom Synthesis: Serves as a specialized starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Library Synthesis: Utilized for creating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	tert-Butyl 4-(3-Nitrobenzylamino)Piperidine-1-Carboxylate
CAS No.	1233952-99-2
Molecular Formula	C17H25N3O4
Molecular Weight	335.40 g/mol
Synonyms	1-Boc-4-[(3-nitrobenzyl)amino]piperidine; 4-[(3-Nitrobenzyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-[(3-nitrobenzyl)amino]piperidine-1-carboxylate; 1,1-Dimethylethyl 4-[(3-nitrobenzyl)amino]-1-piperidinecarboxylate; 4-(3-Nitrobenzylamino)piperidine-1-carboxylic acid tert-butyl ester; N-(3-Nitrobenzyl)-N-(1-Boc-piperidin-4-yl)amine; 1-Boc-4-(3-nitrobenzylamino)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Nitrobenzylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.