Description

tert-Butyl 4-[(Pyrrolidine-1-Carbonyl)Amino]Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine core modified with a pyrrolidine carboxamide group and protected by a tert-butoxycarbonyl (Boc) moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential biological activity. It is primarily utilized by pharmaceutical companies and research institutions in the synthesis of novel drug candidates, particularly in areas targeting the central nervous system and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of protease inhibitors due to its piperidine-pyrrolidine scaffold.
• Kinase Inhibitor Development: Employed in the construction of heterocyclic cores for potential kinase inhibitor libraries.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 4-[(Pyrrolidine-1-Carbonyl)Amino]Piperidine-1-Carboxylate
CAS No.	1233952-82-3
Molecular Formula	C15H27N3O3
Molecular Weight	297.40 g/mol
Synonyms	1-Boc-4-(pyrrolidine-1-carboxamido)piperidine; 1-(tert-Butoxycarbonyl)-4-[(pyrrolidine-1-carbonyl)amino]piperidine; 4-(Pyrrolidine-1-carbonylamino)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(pyrrolidine-1-carboxamido)piperidine-1-carboxylate; 4-(1-Pyrrolidinecarboxamido)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; BOC-4-(Pyrrolidinecarboxamido)piperidine; 1233952-82-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[(Pyrrolidine-1-Carbonyl)Amino]Piperidine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.