Description

1-(3-Fluorophenyl)-3-(Piperidin-4-Yl)Urea Hydrochloride is a high-purity, fluorinated urea derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological intermediate and building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical companies and contract research organizations (CROs) engaged in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new chemical entities (NCEs) for clinical trials.
• Kinase Inhibitor Research: Used as a core scaffold or fragment in the design and synthesis of potential kinase inhibitors.
• CNS Drug Discovery: Employed in medicinal chemistry programs aimed at creating novel therapeutics for neurological and psychiatric conditions.
• Chemical Biology Probes: Serves as a building block for creating tool compounds to study specific biological pathways and protein functions.
• Process Chemistry & Scale-Up: Utilized in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	1-(3-Fluorophenyl)-3-(Piperidin-4-Yl)Urea Hydrochloride
CAS No.	1233952-56-1
Molecular Formula	C12H16FN3O · HCl
Molecular Weight	273.74 g/mol (Free base: 237.28 g/mol)
Synonyms	1-(3-Fluorophenyl)-3-(4-Piperidinyl)urea hydrochloride; 3-Fluoro-N-(piperidin-4-yl)phenylurea hydrochloride; 1-(3-Fluorophenyl)-3-(piperidin-4-yl)urea HCl; Urea, N-(3-fluorophenyl)-N'-(4-piperidinyl)-, monohydrochloride; 4-[[(3-Fluorophenyl)amino]carbonylamino]piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(3-Fluorophenyl)-3-(Piperidin-4-Yl)Urea Hydrochloride is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.