Description

n-(Piperidin-4-Yl)Propane-2-Sulfonamidehydrochloride is a high-purity sulfonamide derivative and a key pharmaceutical intermediate. This compound is valued for its role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in oncology and CNS research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the design of protein kinase inhibitors.
• Chemical Synthesis: Employed in organic synthesis for introducing the piperidine-sulfonamide pharmacophore into target molecules.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes for biochemical and pharmacological assays.

Basic Information

Product Name	n-(Piperidin-4-Yl)Propane-2-Sulfonamidehydrochloride
CAS No.	1233952-53-8
Molecular Formula	C8H18N2O2S • HCl
Molecular Weight	254.76 g/mol
Synonyms	4-(2-Isopropylsulfonamido)piperidine hydrochloride; 1-Piperidinepropanesulfonamide, 4-amino-N-(1-methylethyl)-, hydrochloride; 4-Amino-N-isopropylpiperidine-1-sulfonamide hydrochloride; N-Isopropyl-4-aminopiperidine-1-sulfonamide hydrochloride; 4-(Isopropylsulfamoyl)piperidin-1-ium chloride
EINECS	Contact for details

Quality Control

Our n-(Piperidin-4-Yl)Propane-2-Sulfonamidehydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.