Description

tert-Butyl 4-(Nicotinamido)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. This compound is valued for its role as a key building block in the synthesis of complex molecules targeting various therapeutic areas. It is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs) and bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs.
• API Development: Serves as a key structural motif for the construction of complex molecules with potential pharmacological activity.
• Biochemical Research: Used as a reagent in life science research for studying biological pathways and protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke compounds for client projects.
• Library Synthesis: A valuable component for creating diverse chemical libraries used in high-throughput screening for drug discovery.

Basic Information

Product Name	tert-Butyl 4-(Nicotinamido)Piperidine-1-Carboxylate
CAS No.	1233951-99-9
Molecular Formula	C16H23N3O3
Molecular Weight	305.37 g/mol
Synonyms	1-Boc-4-(nicotinamido)piperidine; 1-(tert-Butoxycarbonyl)-4-(nicotinamido)piperidine; 4-(Pyridine-3-carboxamido)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(3-pyridinecarboxamido)piperidine-1-carboxylate; N-(1-Boc-4-piperidyl)nicotinamide; 1233951-99-9; Nicotinamide, N-[1-[(1,1-dimethylethoxy)carbonyl]-4-piperidinyl]-
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(Nicotinamido)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.