Description

1-(4-Fluoro-2-Nitrophenyl)Piperazine Hydrochloride is a high-purity, synthetically valuable organic intermediate characterized by its piperazine and fluoronitrobenzene moieties. This compound is essential for pharmaceutical research and development, serving as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with potential therapeutic or biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated aromatic structure.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and receptor interactions.
• Material Science Research: Investigated as a monomer or building block for advanced polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic & Institutional Research: Used in university and government labs for fundamental organic chemistry and medicinal chemistry studies.

Basic Information

Product Name	1-(4-Fluoro-2-Nitrophenyl)Piperazine Hydrochloride
CAS No.	1233951-86-4
Molecular Formula	C10H11FN4O2·HCl
Molecular Weight	274.68 g/mol
Synonyms	1-(4-Fluoro-2-nitrophenyl)piperazine hydrochloride; 4-Fluoro-2-nitro-1-piperazin-1-ylbenzene hydrochloride; 1-Piperazine, 1-(4-fluoro-2-nitrophenyl)-, hydrochloride; 4-Fluoro-2-nitrophenylpiperazine HCl; 2-Nitro-4-fluorophenylpiperazine hydrochloride; 1-(4-Fluoro-2-nitrophenyl)piperazine HCl salt
EINECS	Contact for details

Quality Control

Our 1-(4-Fluoro-2-Nitrophenyl)Piperazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.