Description

6-Benzyl-2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydropyridopyrimidine class. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Scaffold: Serves as a core structural motif for designing and synthesizing potential kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to create complex heterocyclic compounds for biological screening.

Basic Information

Product Name	6-Benzyl-2-Chloro-5,6,7,8-Tetrahydropyrido[4,3-d]Pyrimidine
CAS No.	1233932-38-1
Molecular Formula	C₁₆H₁₆ClN₃
Molecular Weight	285.77 g/mol
Synonyms	2-Chloro-6-benzyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine; 6-Benzyl-2-chloro-5,6,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidine; 1233932-38-1; 6-Benzyl-2-chloro-4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidine; 2-Chloro-6-benzyl-4H,5H,6H,7H,8H-pyrido[4,3-d]pyrimidine; 6-Benzyl-2-chloro-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine; Benzyl-2-chloro-tetrahydropyridopyrimidine
EINECS	Contact for details

Quality Control

Our 6-Benzyl-2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.