Description

(R)-1-(3-Nitropyridin-2-Yl)Pyrrolidin-3-Amine Hydrochloride is a high-purity chiral amine building block and pharmaceutical intermediate. This compound is of significant value for research and development in medicinal chemistry, particularly in the synthesis of targeted small molecule therapeutics. It is primarily needed by pharmaceutical companies, biotechnology research firms, and advanced contract research organizations (CROs) engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Asymmetric Synthesis: Serves as a chiral amine precursor for constructing complex molecules with defined stereochemistry.
• Chemical Biology Probes: Utilized in the development of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing custom compounds for client projects.
• Library Synthesis: Employed in the generation of focused compound libraries for high-throughput screening.

Basic Information

Product Name	(R)-1-(3-Nitropyridin-2-Yl)Pyrrolidin-3-Amine Hydrochloride
CAS No.	1233859-86-3
Molecular Formula	C9H13ClN4O2
Molecular Weight	244.68 g/mol
Synonyms	(R)-1-(3-Nitropyridin-2-yl)pyrrolidin-3-amine hydrochloride; (R)-3-Amino-1-(3-nitropyridin-2-yl)pyrrolidine hydrochloride; (3R)-1-(3-Nitropyridin-2-yl)pyrrolidin-3-amine hydrochloride; (R)-1-(3-Nitro-2-pyridinyl)-3-pyrrolidinamine hydrochloride; Pyrrolidin-3-amine, 1-(3-nitropyridin-2-yl)-, (3R)-, hydrochloride; 1233859-86-3; (R)-enantiomer of 1-(3-Nitropyridin-2-yl)pyrrolidin-3-amine HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Nitropyridin-2-Yl)Pyrrolidin-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to yellow solid powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.