Description

17-Keto-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid CAS NO 1233715-28-0 is a specialized oxidized metabolite of docosahexaenoic acid (DHA), featuring a unique keto group and specific geometric isomerism. This compound is of significant interest as a high-purity biochemical standard and a key intermediate for advanced research into lipid peroxidation pathways and specialized pro-resolving mediators (SPMs). It is primarily required by pharmaceutical R&D laboratories, analytical reference standard producers, and academic institutions focused on inflammation, neurology, and metabolic studies.

Application

• Biochemical Research Standard: Serves as a critical reference compound for the identification and quantification of DHA-derived oxylipins in biological samples via LC-MS/MS.
• Pharmaceutical Intermediate: Used in the synthesis and development of novel therapeutic agents targeting inflammatory and neurological disorders.
• Metabolic Pathway Studies: A vital tool for investigating the role of specific keto-DHA metabolites in cellular signaling and resolution of inflammation.
• Analytical Method Development: Employed to validate and calibrate analytical methods in lipidomics and metabolomics research.
• Nutraceutical Research: Studied for its potential bioactivity and stability as a derivative of ω-3 fatty acids.

Basic Information

Item	Detail
Product Name	17-Keto-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic Acid
CAS No.	1233715-28-0
Molecular Formula	C22H32O3
Molecular Weight	344.49 g/mol
Synonyms	17-Keto-DHA; 17-Oxo-DHA; 17-oxo-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid; 17-oxo-DHA; (4Z,7Z,10Z,13Z,15E,19Z)-17-oxodocosa-4,7,10,13,15,19-hexaenoic acid; Keto-Derivative of DHA; Oxidized DHA Metabolite
EINECS	Contact for details

Quality Control

Our high-purity biochemical grade 17-Keto-DHA is produced under controlled conditions to ensure batch-to-batch consistency and integrity. Each lot undergoes rigorous analytical testing, including HPLC, GC-MS, and NMR for identity confirmation and purity assessment. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/GC-MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Solubility	Soluble in ethanol, DMSO, and organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.