Description

3-Iodo-6-Trifluoromethyl-Imidazo[1,2-A]Pyridine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound is prized for its unique molecular architecture, which combines an electron-deficient trifluoromethyl group with a reactive iodine substituent on a fused imidazopyridine core. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for targeted therapies and bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the imidazopyridine scaffold.
• Material Science: Serves as a building block for creating specialty chemicals, ligands for catalysis, and advanced organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form new carbon-carbon bonds.
• Functionalization & Derivatization: Enables the introduction of the imidazo[1,2-a]pyridine moiety into more complex molecular systems for structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Iodo-6-Trifluoromethyl-Imidazo[1,2-A]Pyridine
CAS No.	1233690-80-6
Molecular Formula	C8H4F3IN2
Molecular Weight	312.03 g/mol
Synonyms	3-Iodo-6-(trifluoromethyl)imidazo[1,2-a]pyridine; 6-(Trifluoromethyl)-3-iodoimidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine, 3-iodo-6-(trifluoromethyl)-; 3-Iodo-6-trifluoromethylimidazo[1,2-a]pyridine
EINECS	Contact for details

Quality Control

Our production of 3-Iodo-6-Trifluoromethyl-Imidazo[1,2-A]Pyridine adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research and development applications. Each lot is fully characterized and analyzed using advanced techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.