Description

3-Fluoro-2-(Piperazin-1-Yl)Benzonitrile is a high-purity, heterocyclic aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique piperazine and fluorine-substituted benzonitrile structure enables precise molecular design. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the piperazine and fluorine motifs.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for the synthesis of specialized polymers with unique electronic or thermal properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	3-Fluoro-2-(Piperazin-1-Yl)Benzonitrile
CAS No.	1233026-65-7
Molecular Formula	C11H12FN3
Molecular Weight	205.23 g/mol
Synonyms	2-(Piperazin-1-yl)-3-fluorobenzonitrile; 3-Fluoro-2-piperazin-1-ylbenzonitrile; 2-(1-Piperazinyl)-3-fluorobenzonitrile; Benzonitrile, 3-fluoro-2-(1-piperazinyl)-; 1233026-65-7; 3-Fluoro-2-(piperazin-1-yl)benzonitrile; 3-Fluoro-2-piperazinobenzonitrile
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Piperazin-1-Yl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.