Description

4-Piperidinone, 3-Hydroxy-, Hydrochloride is a high-purity, functionalized piperidinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, including central nervous system (CNS) agents, receptor modulators, and enzyme inhibitors.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific stereochemistry for biological activity.
• Fine Chemical Synthesis: Serves as a versatile precursor for creating complex molecules used in catalysis, material science, and specialty polymers.
• Academic & Contract Research: Employed in medicinal chemistry programs and process research for route scouting and optimization studies.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.

Basic Information

Product Name	4-Piperidinone, 3-Hydroxy-, Hydrochloride
CAS No.	1232675-02-3
Molecular Formula	C5H9NO2 • HCl
Molecular Weight	151.59 g/mol (Free base: 115.13 g/mol)
Synonyms	3-Hydroxypiperidin-4-one hydrochloride; 3-Hydroxy-4-piperidinone HCl; 4-Piperidinone, 3-hydroxy-, hydrochloride (1:1); 3-Hydroxy-4-piperidone hydrochloride; 4-Oxo-3-piperidinol hydrochloride; 3-Hydroxy-1,2,5,6-tetrahydropyridin-4-one hydrochloride; 3-Hydroxy-4-piperidone monohydrochloride
EINECS	Contact for details

Quality Control

Every batch of 4-Piperidinone, 3-Hydroxy-, Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure compliance with exacting customer specifications and internal standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.