Description

3-Bromo-6-Fluoropyridin-2-Amine is a high-value, multi-functional halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents on an aromatic amine core, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated pyridines.
• Material Science Research: Employed in the creation of functionalized ligands for catalysis and as a monomer for specialty polymers.
• Chemical Biology & Proteomics: Acts as a versatile scaffold for designing molecular probes and tool compounds for target identification and validation.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Fluorine Chemistry: Serves as a valuable intermediate for introducing fluorine atoms into complex molecules to modulate their lipophilicity, metabolic stability, and binding affinity.

Basic Information

Product Name	3-Bromo-6-Fluoropyridin-2-Amine
CAS No.	1232431-41-2
Molecular Formula	C5H4BrFN2
Molecular Weight	191.00 g/mol
Synonyms	2-Amino-3-bromo-6-fluoropyridine; 6-Fluoro-3-bromopyridin-2-amine; 3-Bromo-6-fluoro-2-pyridinamine; 2-Pyridinamine, 3-bromo-6-fluoro-; 3-Bromo-6-fluoro-2-aminopyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-6-Fluoropyridin-2-Amine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.