Description

5-Bromo-4-Methoxypyridin-2-Amine is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique bromo and methoxy substituents make it a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific pharmacophores or create novel heterocyclic systems.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the pyridine core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological pathways and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable scaffold for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	5-Bromo-4-Methoxypyridin-2-Amine
CAS No.	1232431-11-6
Molecular Formula	C6H7BrN2O
Molecular Weight	203.04 g/mol
Synonyms	2-Amino-5-bromo-4-methoxypyridine; 4-Methoxy-5-bromopyridin-2-amine; 5-Bromo-4-methoxy-2-pyridinamine; 5-Bromo-4-methoxypyridin-2-ylamine; 2-Pyridinamine, 5-bromo-4-methoxy-; (5-Bromo-4-methoxypyridin-2-yl)amine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Methoxypyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.