Description

(E)-2-(5-Bromo-3-Nitropyridin-2-Yl)-N,n-Dimethylethenamine CAS NO 1229457-88-8 is a high-purity, advanced pharmaceutical intermediate characterized by its specific bromo-nitro pyridine core structure. This compound is of critical importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals, where precise molecular architecture is required. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis: Serves as a versatile precursor for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromo substituent.
• Material Science: Potential monomer or functionalizing agent in the creation of specialty polymers and advanced organic materials.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(E)-2-(5-Bromo-3-Nitropyridin-2-Yl)-N,n-Dimethylethenamine
CAS No.	1229457-88-8
Molecular Formula	C11H12BrN3O2
Molecular Weight	298.14 g/mol
Synonyms	(E)-2-(5-Bromo-3-nitropyridin-2-yl)-N,N-dimethylethenamine; 5-Bromo-3-nitro-2-[(E)-2-(dimethylamino)vinyl]pyridine; (E)-N,N-Dimethyl-2-(5-bromo-3-nitropyridin-2-yl)ethen-1-amine; 2-(5-Bromo-3-nitropyridin-2-yl)-N,N-dimethylethenamine (E)-; (E)-1-(Dimethylamino)-2-(5-bromo-3-nitropyridin-2-yl)ethene
EINECS	Contact for details

Quality Control

Our (E)-2-(5-Bromo-3-Nitropyridin-2-Yl)-N,n-Dimethylethenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.