Description

2-Fluoro-5-Methoxy-3-Methylpyridine is a high-purity fluorinated pyridine derivative, a key building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which introduces both fluorine and methoxy groups onto the pyridine scaffold, enabling precise modulation of electronic and steric properties in target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the design and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized organic materials, such as liquid crystals and electronic chemicals.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	2-Fluoro-5-Methoxy-3-Methylpyridine
CAS No.	1228898-05-2
Molecular Formula	C7H8FNO
Molecular Weight	141.14 g/mol
Synonyms	3-Methyl-5-methoxy-2-fluoropyridine; 5-Methoxy-3-methyl-2-fluoropyridine; 2-Fluoro-3-methyl-5-methoxypyridine; 2-Fluoro-5-methoxy-3-picoline; Fluoromethoxymethylpyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-Methoxy-3-Methylpyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.