Description

(5-Bromo-6-Fluoropyridin-3-Yl)Methanol is a high-value pyridine derivative and a versatile chemical building block. Its molecular structure, featuring bromine and fluorine substituents on the pyridine ring, makes it a critical intermediate for synthesizing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries. It enables the construction of novel active ingredients, particularly in the development of new drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings.
• Material Science Research: Employed in the synthesis of organic electronic materials and functionalized polymers due to its modifiable hydroxymethyl group.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes and target engagement.

Basic Information

Product Name	(5-Bromo-6-Fluoropyridin-3-Yl)Methanol
CAS No.	1228897-77-5
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	3-Pyridinemethanol, 5-bromo-6-fluoro-; 5-Bromo-6-fluoro-3-pyridinemethanol; (5-Bromo-6-fluoropyridin-3-yl)methanol; 5-Bromo-6-fluoropyridine-3-methanol; 3-Hydroxymethyl-5-bromo-6-fluoropyridine; 5-Bromo-6-fluoro-3-(hydroxymethyl)pyridine
EINECS	Contact for details

Quality Control

Every batch of (5-Bromo-6-Fluoropyridin-3-Yl)Methanol is manufactured and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, NMR, and GC-MS, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.