Description

4-Benzyl 1-tert-Butyl 2-Oxopiperazine-1,4-Dicarboxylate is a high-purity, protected piperazine derivative of significant importance in advanced organic synthesis. This compound serves as a crucial key building block and intermediate for the development of complex pharmaceutical molecules and bioactive compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing functionalized piperazine scaffolds.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics and constrained peptides for drug discovery programs.
• Medicinal Chemistry: Serves as a versatile building block for creating compound libraries for high-throughput screening against various biological targets.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds to study biological pathways and enzyme functions.
• Process Development: Utilized in route scouting and optimization for the scalable production of target molecules in pilot plants and commercial manufacturing.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) providing bespoke chemical synthesis services.

Basic Information

Product Name	4-Benzyl 1-tert-Butyl 2-Oxopiperazine-1,4-Dicarboxylate
CAS No.	1228675-25-9
Molecular Formula	C17H22N2O5
Molecular Weight	334.37 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-(benzyloxycarbonyl)-2-piperazinone; 1-Boc-4-Cbz-2-piperazinone; tert-Butyl 4-(benzyloxycarbonyl)-2-oxopiperazine-1-carboxylate; 2-Oxo-1,4-piperazinedicarboxylic acid 1-tert-butyl 4-benzyl ester; 4-Cbz-1-Boc-2-piperazinone; 1-N-Boc-4-N-Cbz-2-piperazinone; Piperazine-1,4-dicarboxylic acid, 2-oxo-, 1-(1,1-dimethylethyl) 4-(phenylmethyl) ester
EINECS	Contact for details

Quality Control

Our 4-Benzyl 1-tert-Butyl 2-Oxopiperazine-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.