Description

(1-(6-Fluoropyridin-2-Yl)Pyrrolidin-3-Yl)Methanol CAS NO 1228666-40-7 is a high-purity fluorinated pyrrolidine derivative, a crucial building block in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which combines a fluoropyridine moiety with a pyrrolidine-methanol group, making it an essential intermediate for developing novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new therapeutic agents, particularly in areas like kinase inhibitors and central nervous system (CNS) drugs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in oncology and neurology.
• Kinase Inhibitor Synthesis: Serves as a core structural component in the preparation of potent and selective kinase inhibitors.
• Agrochemical Research: Used in the discovery of advanced pesticides and herbicides, leveraging the bioactivity of the fluoropyridine unit.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands or catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with specific electronic or surface properties.

Basic Information

Product Name	(1-(6-Fluoropyridin-2-Yl)Pyrrolidin-3-Yl)Methanol
CAS No.	1228666-40-7
Molecular Formula	C10H13FN2O
Molecular Weight	196.22 g/mol
Synonyms	1-(6-Fluoropyridin-2-yl)pyrrolidin-3-ylmethanol; 3-(Hydroxymethyl)-1-(6-fluoro-2-pyridinyl)pyrrolidine; (1-(6-Fluoropyridin-2-yl)pyrrolidin-3-yl)methanol; 1-(6-Fluoro-2-pyridyl)-3-pyrrolidinemethanol; 2-(3-(Hydroxymethyl)pyrrolidin-1-yl)-6-fluoropyridine; 6-Fluoro-2-(3-(hydroxymethyl)pyrrolidin-1-yl)pyridine; Fluoropyridine-pyrrolidine methanol derivative
EINECS	Contact for details

Quality Control

Our (1-(6-Fluoropyridin-2-Yl)Pyrrolidin-3-Yl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.