Description

5-Bromo-4-Chloro-3-Iodopyridin-2-Amine is a high-value, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Ligand and Catalyst Development: Used to create complex ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Intermediate for synthesizing functional organic materials, such as organic semiconductors or liquid crystals.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	5-Bromo-4-Chloro-3-Iodopyridin-2-Amine
CAS No.	1228666-03-2
Molecular Formula	C5H3BrClIN2
Molecular Weight	332.35 g/mol
Synonyms	2-Amino-5-bromo-4-chloro-3-iodopyridine; 5-Bromo-4-chloro-3-iodopyridin-2-ylamine; 4-Chloro-5-bromo-3-iodopyridin-2-amine; 3-Iodo-5-bromo-4-chloropyridin-2-amine; 2-Pyridinamine, 5-bromo-4-chloro-3-iodo-; BCI Pyridine Intermediate
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Chloro-3-Iodopyridin-2-Amine is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.