Description

3-(1-Benzylpyrrolidin-3-Yl)-2-Methoxy-5-Methylpyridine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting neurological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold or a functionalized fragment in the construction of complex API molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and receptor binding studies due to its specific pyrrolidine-pyridine structure.
• Fine Chemical Production: Employed in the manufacture of other specialized, high-value fine chemicals and advanced intermediates.

Basic Information

Product Name	3-(1-Benzylpyrrolidin-3-Yl)-2-Methoxy-5-Methylpyridine
CAS No.	1228666-00-9
Molecular Formula	C18H22N2O
Molecular Weight	282.38 g/mol
Synonyms	2-Methoxy-5-methyl-3-(1-benzyl-3-pyrrolidinyl)pyridine; 1-Benzyl-3-(2-methoxy-5-methyl-3-pyridinyl)pyrrolidine; 3-(1-Benzylpyrrolidin-3-yl)-2-methoxy-5-methylpyridine; 5-Methyl-2-methoxy-3-(1-benzyl-3-pyrrolidinyl)pyridine; 1228666-00-9; Benzylpyrrolidinyl methoxymethylpyridine
EINECS	Contact for details

Quality Control

Our 3-(1-Benzylpyrrolidin-3-Yl)-2-Methoxy-5-Methylpyridine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects requiring compliance with cGMP, ICH guidelines, and other relevant regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.