Description

2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine-8-carboxylic acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused dioxino-pyridine carboxylic acid structure. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and drug discovery programs. The compound is supplied with full analytical documentation to ensure batch-to-batch consistency and reliability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Development: Serves as a building block for creating novel herbicides or fungicides with specific modes of action.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Incorporated into molecular probes for studying biological pathways and enzyme functions.

Basic Information

Item	Details
Product Name	2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine-8-carboxylic Acid
CAS No.	1228665-94-8
Molecular Formula	C9H7NO4
Molecular Weight	193.16 g/mol
Synonyms	8-Carboxy-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine; [1,4]Dioxino[2,3-b]pyridine-8-carboxylic acid, 2,3-dihydro-; 2,3-Dihydro-1,4-dioxino[2,3-b]pyridine-8-carboxylic acid; Dioxinopyridine-8-carboxylic acid derivative; CAS 1228665-94-8
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dihydro-[1,4]dioxino[2,3-b]pyridine-8-carboxylic acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and conformity to customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.