Description

2-Fluoro-3,4-Diiodo-6-(Pyrrolidin-1-Yl)Pyridine is a high-purity, multi-halogenated pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in the development of complex molecules, offering unique reactivity due to its fluorine and iodine substituents. It is primarily utilized by pharmaceutical and agrochemical R&D teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution, facilitated by the iodine and fluorine atoms.
• Ligand Development: The pyrrolidinyl and halogen groups make it a candidate for developing novel ligands in catalysis and metal-organic frameworks (MOFs).
• Life Science Probes: Potential use in creating fluorescent or radiolabeled probes for biochemical and diagnostic applications.

Basic Information

Product Name	2-Fluoro-3,4-Diiodo-6-(Pyrrolidin-1-Yl)Pyridine
CAS No.	1228665-88-0
Molecular Formula	C9H7F I2N2
Molecular Weight	415.97 g/mol
Synonyms	2-Fluoro-3,4-diiodo-6-(1-pyrrolidinyl)pyridine; 6-(Pyrrolidin-1-yl)-2-fluoro-3,4-diiodopyridine; 3,4-Diiodo-2-fluoro-6-pyrrolidin-1-ylpyridine; 2-Fluoro-3,4-diiodo-6-pyrrolidin-1-yl-pyridine; 1228665-88-0; FC(I)(I)C1=C(N=C(C=N1)N2CCCC2)F
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3,4-Diiodo-6-(Pyrrolidin-1-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.