Description

1-(6-Iodo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazin-1-Yl)-2,2-Dimethylpropan-1-One is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for the development of novel pharmaceutical candidates, particularly in medicinal chemistry research targeting central nervous system and oncological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel drug candidates, especially in neurological and oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Serves as a key intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke synthesis services.
• Academic Research: Employed in university and institutional labs for pioneering research in organic methodology and heterocyclic chemistry.

Basic Information

Product Name	1-(6-Iodo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazin-1-Yl)-2,2-Dimethylpropan-1-One
CAS No.	1228665-79-9
Molecular Formula	C₁₃H₁₅IN₂O₂
Molecular Weight	358.18 g/mol
Synonyms	1-(6-Iodo-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-1-yl)-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-(6-iodo-1,4-dihydro-2H-pyrido[2,3-b][1,4]oxazin-1-yl)propan-1-one; 6-Iodo-1-(2,2-dimethylpropanoyl)-1,4-dihydro-2H-pyrido[2,3-b][1,4]oxazine; Pivaloyl-6-iodo-1,4-dihydro-2H-pyrido[2,3-b][1,4]oxazine; CAS 1228665-79-9
EINECS	Contact for details

Quality Control

Our 1-(6-Iodo-2,3-Dihydro-1H-Pyrido[2,3-B][1,4]Oxazin-1-Yl)-2,2-Dimethylpropan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C (refrigerated) for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.