Description

tert-Butyl 2-Fluoro-6-(Pyrrolidin-1-Yl)Pyridin-3-Ylcarbamate is a high-value, multi-functional chemical intermediate featuring a unique fluorinated pyridine core. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors seeking to incorporate fluorinated heterocyclic motifs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, where the fluorine atom and pyridine structure can enhance biological activity and stability.
• Ligand Synthesis: Acts as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Fluorinated Building Block: Employed in medicinal chemistry for scaffold hopping and bioisosteric replacement to optimize the pharmacokinetic properties of lead compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with specific electronic or surface properties.

Basic Information

Product Name	tert-Butyl 2-Fluoro-6-(Pyrrolidin-1-Yl)Pyridin-3-Ylcarbamate
CAS No.	1228665-71-1
Molecular Formula	C14H20FN3O2
Molecular Weight	281.33 g/mol
Synonyms	Carbamic acid, N-(2-fluoro-6-(1-pyrrolidinyl)-3-pyridinyl)-, 1,1-dimethylethyl ester; tert-Butyl N-[2-fluoro-6-(pyrrolidin-1-yl)pyridin-3-yl]carbamate; 1,1-Dimethylethyl N-[2-fluoro-6-(1-pyrrolidinyl)-3-pyridinyl]carbamate; 2-Fluoro-6-(pyrrolidin-1-yl)pyridin-3-amine, N-Boc protected; Boc-2-fluoro-6-(pyrrolidin-1-yl)pyridin-3-amine; 1228665-71-1
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Fluoro-6-(Pyrrolidin-1-Yl)Pyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.