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6-(3-Iodopyridin-2-Yloxy)Furo[3,2-B]Pyridine CAS NO 1228665-68-6
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CAS No.:1228665-68-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-(3-Iodopyridin-2-Yloxy)Furo[3,2-B]Pyridine is a high-purity, advanced heterocyclic building block and pharmaceutical intermediate. This compound is of significant value for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.
Application
- Pharmaceutical Intermediate: A key synthon in the synthesis of targeted kinase inhibitors and other small molecule therapeutics.
- Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its fused heterocyclic scaffold.
- Agrochemical Development: Serves as a building block for creating novel crop protection agents with specific biological activity.
- Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and cellular pathways.
- Organic Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and other transformations to create complex polycyclic systems.
- Material Science Research: Potential precursor for organic electronic materials due to its conjugated π-system.
Basic Information
| Product Name | 6-(3-Iodopyridin-2-Yloxy)Furo[3,2-B]Pyridine |
| CAS No. | 1228665-68-6 |
| Molecular Formula | C12H7IN2O2 |
| Molecular Weight | 338.10 g/mol |
| Synonyms | 6-[(3-Iodopyridin-2-yl)oxy]furo[3,2-b]pyridine; 6-(3-Iodopyridin-2-yloxy)furo[3,2-b]pyridine; Furo[3,2-b]pyridine, 6-[(3-iodo-2-pyridinyl)oxy]-; 6-(3-Iodo-2-pyridyloxy)furo[3,2-b]pyridine; 1228665-68-6; AI3-72093; SCHEMBL21826527; ZINC000253899977 |
| EINECS | Contact for details |
Quality Control
Our 6-(3-Iodopyridin-2-Yloxy)Furo[3,2-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to maximize long-term stability. Handle and store in accordance with all applicable laboratory safety practices.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Single Unknown Impurity (HPLC) | ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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