Description

Benzyl 3,5-Dioxopiperidine-1-Carboxylate is a high-purity synthetic intermediate belonging to the piperidine-dione class of compounds. Its value lies in its role as a versatile building block for the synthesis of more complex molecules, particularly in pharmaceutical research and development. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the piperidine or glutarimide core structures.
• Proteasome Inhibitor Research: Serves as a precursor in the development and study of proteasome inhibitors, a class of compounds with therapeutic potential in oncology.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the construction of novel heterocyclic compounds for biological screening.
• Agrochemical Synthesis: Employed as an intermediate in the production of advanced crop protection agents and pesticides.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of specialty chemicals requiring high-purity, complex intermediates.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) engaged in synthetic organic chemistry and drug discovery projects.

Basic Information

Product Name	Benzyl 3,5-Dioxopiperidine-1-Carboxylate
CAS No.	1228631-19-3
Molecular Formula	C13H13NO4
Molecular Weight	247.25 g/mol
Synonyms	1-(Benzyloxycarbonyl)-3,5-piperidinedione; 1-CBZ-3,5-piperidinedione; Benzyl 3,5-dioxo-1-piperidinecarboxylate; 1-[(Benzyloxy)carbonyl]piperidine-3,5-dione; N-CBZ-3,5-piperidinedione; 3,5-Dioxo-1-piperidinecarboxylic acid phenylmethyl ester; 1-Piperidinecarboxylic acid, 3,5-dioxo-, phenylmethyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 3,5-Dioxopiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.