Description

(7R)-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-7-Amine is a high-purity chiral amine building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. Pharmaceutical R&D teams and fine chemical manufacturers need it for its stereochemical integrity and functional group versatility, enabling the synthesis of novel therapeutic candidates and specialty materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex, enantiomerically pure molecules in academic and industrial research.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands and organocatalysts for stereoselective transformations.
• Agrochemical Research: Employed as an intermediate in the synthesis of advanced, biologically active compounds for crop protection.
• Material Science: A precursor for specialty polymers and advanced organic materials requiring specific chiral motifs.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	(7R)-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-7-Amine
CAS No.	1228571-16-1
Molecular Formula	C8H10N2
Molecular Weight	134.18 g/mol
Synonyms	(7R)-6,7-Dihydro-5H-cyclopenta[b]pyridin-7-amine; (7R)-7-Amino-6,7-dihydro-5H-cyclopenta[b]pyridine; (R)-6,7-Dihydro-5H-cyclopenta[b]pyridin-7-amine; (R)-7-Amino-6,7-dihydro-5H-cyclopenta[b]pyridine; 5H-Cyclopenta[b]pyridin-7-amine, 6,7-dihydro-, (7R)-; Chiral Cyclopentapyridinamine; (7R)-Aminocyclopentapyridine
EINECS	Contact for details

Quality Control

Our (7R)-6,7-Dihydro-5H-Cyclopenta[B]Pyridin-7-Amine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including HPLC purity, chiral purity (enantiomeric excess), and residual solvent analysis, in line with ICH guidelines. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.