Description

(S)-2-(3-Fluorophenyl)Piperidine CAS NO 1228542-46-8 is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical and agrochemical research. Its value lies in its unique stereochemistry and fluorinated aromatic ring, which are essential for modulating the biological activity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by medicinal chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of central nervous system (CNS) drugs, receptor modulators, and enzyme inhibitors.
• Agrochemical Synthesis: Building block for creating novel pesticides and herbicides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Serves as a core structure for developing molecular probes to study biological pathways and protein function.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for commercial drug manufacturing.
• Academic & Institutional Research: Used in universities and research institutes for exploratory synthetic chemistry and drug discovery projects.

Basic Information

Product Name	(S)-2-(3-Fluorophenyl)Piperidine
CAS No.	1228542-46-8
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	(S)-2-(3-Fluorophenyl)piperidine; (S)-2-(3-Fluorophenyl)piperidine; (3S)-2-(3-Fluorophenyl)piperidine; (S)-2-(3-Fluorophenyl)piperidine; (S)-2-(3-Fluorophenyl)piperidine hydrochloride; (S)-2-(3-Fluorophenyl)piperidine HCL; 1228542-46-8; (S)-2-(m-Fluorophenyl)piperidine
EINECS	Contact for details

Quality Control

Our (S)-2-(3-Fluorophenyl)Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, NMR, and LC-MS, to ensure identity, purity, and enantiomeric excess meet stringent specifications. Certificates of Analysis (COA) with full traceability are provided for each lot, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.