Description

1-tert-Butyl 2-Methyl 3,6-Dihydropyridine-1,2(2H)-Dicarboxylate is a high-purity, protected dihydropyridine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex nitrogen-containing heterocycles, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those containing piperidine or related nitrogen heterocycles.
• Agrochemical Synthesis: Used in research and development for creating novel pesticides and herbicides with specific biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for introducing protected amine functionalities in multi-step synthetic routes.
• Chemical Research: Essential material for methodological studies in academic and industrial R&D labs focusing on heterocyclic chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high-purity intermediates.

Basic Information

Product Name	1-tert-Butyl 2-Methyl 3,6-Dihydropyridine-1,2(2H)-Dicarboxylate
CAS No.	1228430-37-2
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	tert-Butyl methyl 3,6-dihydro-2H-pyridine-1,2-dicarboxylate; 1-(tert-Butoxycarbonyl)-2-(methoxycarbonyl)-1,2,3,6-tetrahydropyridine; Boc-2-(COOMe)-1,2,3,6-tetrahydropyridine; 1-Boc-2-(methoxycarbonyl)-1,2,3,6-tetrahydropyridine; Methyl 1-(tert-butoxycarbonyl)-1,2,3,6-tetrahydropyridine-2-carboxylate; 3,6-Dihydro-2H-pyridine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester; 1,2,3,6-Tetrahydropyridine-1,2-dicarboxylic acid 1-tert-butyl 2-methyl ester
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 2-Methyl 3,6-Dihydropyridine-1,2(2H)-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.