Description

H2N-PEG13-CH2CH2NH2 CAS NO 1228119-65-0 is a heterobifunctional polyethylene glycol (PEG) linker featuring a primary amine at one terminus and a diamine group at the other, connected by a 13-unit PEG spacer. This structure is critical for creating stable, hydrophilic, and flexible conjugates in advanced bioconjugation and nanomaterial synthesis. It is an essential building block for researchers and manufacturers in pharmaceuticals, diagnostics, and materials science who require precise, water-soluble crosslinking agents. The compound's dual-reactive handles enable the controlled attachment of biomolecules, polymers, or surfaces while imparting beneficial PEGylation properties.

Application

• Bioconjugation and Protein Modification: Used to crosslink proteins, antibodies, or peptides with other biomolecules, drugs, or solid surfaces, enhancing solubility and stability.
• Drug Delivery System Development: Serves as a key component in constructing PEGylated liposomes, nanoparticles, and polymer-drug conjugates to improve pharmacokinetics.
• Diagnostic Reagent Synthesis: Employed in the preparation of fluorescent probes, enzyme labels, and other diagnostic conjugates where a hydrophilic spacer is required.
• Surface Functionalization: Facilitates the amine-reactive modification of biosensor chips, microarrays, and other material surfaces for biomolecule immobilization.
• Hydrogel and Biomaterial Fabrication: Acts as a crosslinker or functional component in the synthesis of biocompatible hydrogels and scaffolds for tissue engineering.
• Polymer Chemistry: Utilized as a macroinitiator or chain extender in the synthesis of functional, amphiphilic block copolymers.

Basic Information

Product Name	H2N-PEG13-CH2CH2NH2
CAS No.	1228119-65-0
Molecular Formula	C30H64N2O13
Molecular Weight	636.8 g/mol
Synonyms	α-Amino-ω-(2-aminoethyl)tetraethylene glycol undecaethylene glycol ether; Amine-PEG13-ethylenediamine; 2,5,8,11,14,17,20,23,26,29,32,35,38-Tridecaoxatetracontane-1,40-diamine; NH2-PEG13-C2-NH2; Heterobifunctional PEG Amine, 13-mer; PEG13 diamine linker; Amino-PEG13-ethylamine
EINECS	Contact for details

Quality Control

Our H2N-PEG13-CH2CH2NH2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity standards suitable for research and bioconjugation applications. Certificates of Analysis (COA) detailing purity, identity, and moisture content are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere (argon or nitrogen), consider desiccation to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Molecular Weight Confirmation (MS)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.