Description

tert-Butyl 2-Bromo-6-Chloropyridin-3-Ylcarbamate is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a protected amine group and reactive halogen sites, enabling precise molecular construction for complex target compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require reliable, high-quality raw materials for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the pyridine core is a common bioactive scaffold.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or photoactive compounds.
• Custom Chemical Synthesis: A versatile building block for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional labs for methodological development and exploring new chemical reactions.

Basic Information

Item	Details
Product Name	tert-Butyl 2-Bromo-6-Chloropyridin-3-Ylcarbamate
CAS No.	1227958-32-8
Molecular Formula	C10H12BrClN2O2
Molecular Weight	307.57 g/mol
Synonyms	tert-Butyl N-(2-bromo-6-chloropyridin-3-yl)carbamate; 2-Bromo-6-chloro-3-pyridinylcarbamic acid 1,1-dimethylethyl ester; 3-((tert-Butoxycarbonyl)amino)-2-bromo-6-chloropyridine; Boc-2-Bromo-6-chloro-3-aminopyridine; 2-Bromo-6-chloro-3-Boc-aminopyridine; tert-Butyl (2-bromo-6-chloro-3-pyridinyl)carbamate; 2-Bromo-6-chloro-pyridin-3-yl-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-6-Chloropyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.