Description

tert-Butyl 4-[2-(2-Bromo-4-Fluorophenoxy)-Ethyl]Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery and development. Its core value lies in its role as a versatile building block for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. This compound is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of novel small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) drugs.
• Drug Discovery & Medicinal Chemistry: Used in research and development for creating and optimizing lead compounds, enabling structure-activity relationship (SAR) studies.
• Custom Synthesis: Serves as a key starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Library Synthesis: Employed in the generation of diverse chemical libraries for high-throughput screening against various biological targets.

Basic Information

Product Name	tert-Butyl 4-[2-(2-Bromo-4-Fluorophenoxy)-Ethyl]Piperazine-1-Carboxylate
CAS No.	1227955-27-2
Molecular Formula	C17H24BrFN2O3
Molecular Weight	403.29 g/mol
Synonyms	1-Boc-4-[2-(2-Bromo-4-fluorophenoxy)ethyl]piperazine; 1-(tert-Butoxycarbonyl)-4-[2-(2-bromo-4-fluorophenoxy)ethyl]piperazine; tert-Butyl 4-(2-(2-bromo-4-fluorophenoxy)ethyl)piperazine-1-carboxylate; 4-[2-(2-Bromo-4-fluorophenoxy)ethyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; BOC-4-(2-(2-Bromo-4-fluorophenoxy)ethyl)piperazine; 1227955-27-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-[2-(2-Bromo-4-Fluorophenoxy)-Ethyl]Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.