Description

Methyl 2-Chloro-6-Piperidin-1-Ylisonicotinate CAS NO 1227955-17-0 is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine and piperidine substitution pattern. This compound is of significant value for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, especially those targeting neurological and oncological pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within R&D laboratories.
• Agrochemical Development: Serves as a building block for creating new active ingredients in crop protection products.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic frameworks due to its reactive chloro and ester functional groups.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	Methyl 2-Chloro-6-Piperidin-1-Ylisonicotinate
CAS No.	1227955-17-0
Molecular Formula	C12H15ClN2O2
Molecular Weight	254.71 g/mol
Synonyms	Methyl 2-chloro-6-(piperidin-1-yl)isonicotinate; 2-Chloro-6-(1-piperidinyl)isonicotinic acid methyl ester; Methyl 2-chloro-6-(1-piperidinyl)isonicotinate; 2-Chloro-6-piperidin-1-yl-isonicotinic acid methyl ester; Methyl 2-chloro-6-piperidin-1-ylpyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-chloro-6-(1-piperidinyl)-, methyl ester; 1227955-17-0
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-6-Piperidin-1-Ylisonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.