Description

3-{4-[3-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepan-1-Yl}Propanoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure with a trifluoromethyl group. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules targeting the central nervous system. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for creating potential drug candidates, especially in areas like neurology and psychiatry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) and improve drug-like properties.
• Preclinical Drug Development: Serves as a critical precursor for producing compounds for pharmacological screening, pharmacokinetic studies, and toxicology assessments.
• Library Synthesis: Employed in the generation of focused chemical libraries for high-throughput screening against biological targets.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academics & Biotechnology: Utilized in university and biotech research labs for fundamental studies in organic synthesis and bioorganic chemistry.

Basic Information

Product Name	3-{4-[3-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepan-1-Yl}Propanoic Acid
CAS No.	1227955-01-2
Molecular Formula	C15H18F3N3O2
Molecular Weight	329.32 g/mol
Synonyms	3-[4-[3-(Trifluoromethyl)-2-pyridinyl]-1,4-diazepan-1-yl]propanoic acid; 1,4-Diazepane-1-propanoic acid, 4-[3-(trifluoromethyl)-2-pyridinyl]-; 1227955-01-2; 3-(4-(3-(Trifluoromethyl)pyridin-2-yl)-1,4-diazepan-1-yl)propanoic acid; 3-(4-(3-(Trifluoromethyl)-2-pyridinyl)-1,4-diazepan-1-yl)propanoic acid; 3-(4-(3-(Trifluoromethyl)pyridin-2-yl)-1,4-diazepan-1-yl)propionic acid
EINECS	Contact for details

Quality Control

Our production of 3-{4-[3-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepan-1-Yl}Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are fully characterized and undergo rigorous analytical testing. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.