Description

1-[6-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepane is a high-value, nitrogen-containing heterocyclic compound featuring a diazepane core linked to a trifluoromethyl-substituted pyridine moiety. This unique structure makes it a critical pharmaceutical intermediate and building block for medicinal chemistry research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, enzyme inhibitors, and receptor modulators.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its privileged diazepane scaffold and fluorine substitution.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides, leveraging the biological activity of the diazepane ring.
• Chemical Biology Probes: Utilized in the development of molecular probes and tool compounds for studying biological pathways and target validation.
• Ligand Synthesis for Catalysis: Can be employed to create novel nitrogen-donor ligands for transition metal catalysis in fine chemical synthesis.
• Advanced Material Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials where its aromatic and aliphatic amine functionalities are valuable.

Basic Information

Product Name	1-[6-(Trifluoromethyl)Pyridin-2-Yl]-1,4-Diazepane
CAS No.	1227954-88-2
Molecular Formula	C11H14F3N3
Molecular Weight	245.25 g/mol
Synonyms	2-(1,4-Diazepan-1-yl)-6-(trifluoromethyl)pyridine; 1,4-Diazepane, 1-[6-(trifluoromethyl)-2-pyridinyl]-; 6-(Trifluoromethyl)-2-(1,4-diazepan-1-yl)pyridine; 1-(6-(Trifluoromethyl)pyridin-2-yl)-1,4-diazepane; 2-(1,4-Diazepan-1-yl)-6-trifluoromethylpyridine; 1,4-Diazepane, 1-(6-(trifluoromethyl)-2-pyridinyl)-; 1-(6-(Trifluoromethyl)-2-pyridyl)-1,4-diazepane
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95% (Standard Grade)
Purity (HPLC)	≥ 98% (High Purity Grade)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.