Description

3-{4-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Piperazin-1-Yl}Propanoic Acid is a high-value, functionalized piperazine derivative that serves as a critical building block in modern organic synthesis. This compound is engineered to provide a versatile chemical handle for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for research chemists and process development scientists working on novel active ingredients, offering a unique combination of a halogenated pyridine ring and a carboxylic acid-terminated piperazine linker.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethylpyridine moiety.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probe Development: The carboxylic acid group allows for facile conjugation to biomolecules, making it useful for creating tool compounds and probes.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	3-{4-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Piperazin-1-Yl}Propanoic Acid
CAS No.	1227954-73-5
Molecular Formula	C13H13ClF3N3O2
Molecular Weight	335.71 g/mol
Synonyms	3-[4-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-1-piperazinyl]propanoic acid; 2-Piperazinepropanoic acid, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-4-(2-carboxyethyl)piperazine; 3-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)propanoic acid; CAS 1227954-73-5
EINECS	Contact for details

Quality Control

Our production of 3-{4-[3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl]Piperazin-1-Yl}Propanoic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.