Description

tert-Butyl 4-[2-(3-Bromophenoxy)-Ethyl]Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with a bromophenoxyethyl side chain. This compound is valued for its role as a versatile building block in modern organic synthesis, enabling the development of complex molecules with targeted biological activity. It is primarily required by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting receptor modulation.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex molecular architectures via reactions at the piperazine nitrogen or the bromoaryl site.
• Research & Development (R&D): Essential for academic and industrial research programs focused on developing new chemical entities and exploring structure-activity relationships (SAR).
• Agrochemical Synthesis: Potential intermediate in the development of advanced crop protection agents and pesticides.
• Material Science Research: Can serve as a monomer or functional component in the synthesis of specialty polymers and advanced materials.

Basic Information

Product Name	tert-Butyl 4-[2-(3-Bromophenoxy)-Ethyl]Piperazine-1-Carboxylate
CAS No.	1227954-64-4
Molecular Formula	C17H25BrN2O3
Molecular Weight	385.30 g/mol
Synonyms	1-Boc-4-[2-(3-bromophenoxy)ethyl]piperazine; tert-Butyl 4-(2-(3-bromophenoxy)ethyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[2-(3-bromophenoxy)ethyl]piperazine; 4-[2-(3-Bromophenoxy)ethyl]-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; BOC-4-(2-(3-Bromophenoxy)ethyl)piperazine; 1227954-64-4; Piperazine, 1-[2-(3-bromophenoxy)ethyl]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-[2-(3-Bromophenoxy)-Ethyl]Piperazine-1-Carboxylate adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.