Description

tert-Butyl 4-(4-Cyanopyridin-2-Yl)-1,4-Diazepane-1-Carboxylate CAS NO 1227954-63-3 is a high-purity, protected diazepane derivative featuring a cyanopyridine moiety, serving as a critical advanced pharmaceutical intermediate. This compound is essential for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, especially those with diazepane-based scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• CNS Drug Development: Potential precursor for compounds targeting neurological receptors and enzymes.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological pathways.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of specialized, high-value intermediates.
• Library Synthesis: Valuable for generating diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	tert-Butyl 4-(4-Cyanopyridin-2-Yl)-1,4-Diazepane-1-Carboxylate
CAS No.	1227954-63-3
Molecular Formula	C16H22N4O2
Molecular Weight	302.37 g/mol
Synonyms	1,4-Diazepane-1-carboxylic acid, 4-(4-cyano-2-pyridinyl)-, 1,1-dimethylethyl ester; 1-Boc-4-(4-cyanopyridin-2-yl)-1,4-diazepane; tert-Butyl 4-(4-cyano-2-pyridyl)-1,4-diazepane-1-carboxylate; 4-(4-Cyanopyridin-2-yl)-1,4-diazepane-1-carboxylic acid tert-butyl ester; Boc-4-(4-cyanopyridin-2-yl)-1,4-diazepane; 1227954-63-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(4-Cyanopyridin-2-Yl)-1,4-Diazepane-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All batches are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.