Description

1-tert-Butoxycarbonyl-4-[2-(Pyrazol-3-Yl)Phenoxy]Ethylpiperazine is a high-purity, advanced pharmaceutical intermediate featuring a complex molecular architecture combining piperazine, pyrazole, and phenoxy moieties. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, custom synthesis providers, and agrochemical innovators seeking to build sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material or intermediate for the custom production of complex molecules under cGMP conditions.
• Agrochemical Development: Potential intermediate in the research and synthesis of new-generation crop protection agents with specific biological activity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target engagement.
• Academic & Institutional Research: Employed in university and research institute laboratories for exploratory organic synthesis and method development.

Basic Information

Product Name	1-tert-Butoxycarbonyl-4-[2-(Pyrazol-3-Yl)Phenoxy]Ethylpiperazine
CAS No.	1227954-41-7
Molecular Formula	C20H28N4O3
Molecular Weight	372.47 g/mol
Synonyms	1-Boc-4-[2-(1H-pyrazol-3-yl)phenoxy]ethylpiperazine; 4-[2-(1H-Pyrazol-3-yl)phenoxy]ethyl-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-[2-(1H-pyrazol-3-yl)phenoxy]ethylpiperazine-1-carboxylate; BOC-Pyrazolylphenoxylethylpiperazine; 1227954-41-7; 1-tert-Butoxycarbonyl-4-(2-(1H-pyrazol-3-yl)phenoxy)ethylpiperazine
EINECS	Contact for details

Quality Control

Our production of 1-tert-Butoxycarbonyl-4-[2-(Pyrazol-3-Yl)Phenoxy]Ethylpiperazine adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical R&D and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support development under quality agreements and can tailor purity grades to meet specific project requirements, from research (>95%) to advanced intermediate (>98%) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Standard Research Grade)
Purity (HPLC)	≥ 98.0% (Advanced Intermediate Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.