Description

tert-Butyl 4-{2-[(2-Chloropyridin-3-Yl)-Oxy]Ethyl}Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). Its core value lies in its role as a critical building block, enabling the precise construction of molecules with specific biological activity. This compound is essential for research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries, particularly those focused on developing new therapeutic agents or crop protection products.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the chloropyridine moiety for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Supplied in consistent quality for process development and pilot-scale manufacturing of target APIs.
• Custom Synthesis Building Block: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.

Basic Information

Product Name	tert-Butyl 4-{2-[(2-Chloropyridin-3-Yl)-Oxy]Ethyl}Piperazine-1-Carboxylate
CAS No.	1227954-32-6
Molecular Formula	C16H24ClN3O3
Molecular Weight	341.84 g/mol
Synonyms	1-Boc-4-[2-[(2-chloropyridin-3-yl)oxy]ethyl]piperazine; tert-Butyl 4-(2-((2-chloropyridin-3-yl)oxy)ethyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-[2-[(2-chloro-3-pyridinyl)oxy]ethyl]piperazine; 4-[2-[(2-Chloropyridin-3-yl)oxy]ethyl]piperazine-1-carboxylic acid tert-butyl ester; 1227954-32-6; Boc-protected chloropyridinyloxyethyl piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-{2-[(2-Chloropyridin-3-Yl)-Oxy]Ethyl}Piperazine-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, supporting your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.