Description

5-Bromo-1H-Pyrazolo[4,3-B]Pyridine is a high-value brominated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound matters because it serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and crop protection agents, enabling the exploration of new therapeutic and biological pathways. It is primarily needed by medicinal chemists and process development scientists in pharmaceutical R&D, agrochemical companies, and advanced material science laboratories focused on creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides with potential for improved efficacy.
• Chemical Biology Probe: Serves as a versatile scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and ligands for catalysis.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process optimization for client projects.

Basic Information

Product Name	5-Bromo-1H-Pyrazolo[4,3-B]Pyridine
CAS No.	1227628-78-5
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-1H-pyrazolo[4,3-b]pyridine; 5-Bromo-1H-pyrazolo[4,3-b]pyridin; 5-Bromo-1H-pyrazolo[4,3-b]pyridine; 5-Bromo-1H-pyrazolo[4,3-b]pyridine; 1227628-78-5; 5-Bromo-1H-pyrazolo[4,3-b]pyridine; 5-Bromo-1H-pyrazolo[4,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Pyrazolo[4,3-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality commitment aligns with the standards expected for pharmaceutical intermediates, including compliance with relevant ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.