Description

5-Fluoro-6-Trifluoromethyl-Pyridin-2-Ylamine is a high-value, multi-fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl substituents, is engineered to impart desirable properties such as metabolic stability, lipophilicity, and enhanced binding affinity in target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine motifs contribute to efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic components.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and linkers for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	5-Fluoro-6-Trifluoromethyl-Pyridin-2-Ylamine
CAS No.	1227602-80-3
Molecular Formula	C7H4F4N2
Molecular Weight	192.11 g/mol
Synonyms	2-Amino-5-fluoro-6-(trifluoromethyl)pyridine; 5-Fluoro-6-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 5-fluoro-6-(trifluoromethyl)-; 5-Fluoro-6-trifluoromethyl-2-aminopyridine; 5-Fluoro-6-trifluoromethyl-pyridin-2-ylamine; 1227602-80-3; 5-Fluoro-6-(trifluoromethyl)-2-pyridinamine
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Trifluoromethyl-Pyridin-2-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.