Description

3-Pyridinamine, 2-Fluoro-6-Methoxy- is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and methoxy substituents, provides valuable electronic and steric properties for modulating the activity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for improved metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis and organocatalysts due to its electron-withdrawing and donating groups.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Scale-up: Available for contract research organizations (CROs) and custom manufacturing organizations (CMOs) for process development and commercial-scale production.

Basic Information

Item	Detail
Product Name	3-Pyridinamine, 2-Fluoro-6-Methoxy-
CAS No.	1227602-55-2
Molecular Formula	C6H7FN2O
Molecular Weight	142.13 g/mol
Synonyms	2-Fluoro-6-methoxypyridin-3-amine; 3-Amino-2-fluoro-6-methoxypyridine; 2-Fluoro-6-methoxy-3-pyridinamine; 2-Fluoro-6-methoxy-3-aminopyridine; 2-Fluoro-6-methoxypyridin-3-ylamine; 2-Fluoro-6-methoxy-3-pyridylamine
EINECS	Contact for details

Quality Control

Every batch of 3-Pyridinamine, 2-Fluoro-6-Methoxy- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.