Description

3-Chloro-2-Hydroxy-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its unique halogenated and trifluoromethylated pyridine core. This compound is essential for advanced chemical synthesis, offering significant potential for modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new small-molecule drugs.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Employed in the synthesis of advanced organic materials, such as liquid crystals or electronic chemicals.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	3-Chloro-2-Hydroxy-4-(Trifluoromethyl)Pyridine
CAS No.	1227602-53-0
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	3-Chloro-4-(trifluoromethyl)pyridin-2-ol; 2-Hydroxy-3-chloro-4-(trifluoromethyl)pyridine; 3-Chloro-2-hydroxy-4-trifluoromethylpyridine; 4-(Trifluoromethyl)-3-chloropyridin-2-ol; 3-Chloro-4-(trifluoromethyl)-2-pyridinol; 2-Pyridinol, 3-chloro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Hydroxy-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.