Description

2-Chloro-6-(Trifluoromethyl)Pyridin-4-Ol is a high-value, halogenated pyridine derivative serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides exceptional reactivity and physicochemical properties for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic pathways.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Pyridin-4-Ol
CAS No.	1227602-42-7
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	4-Hydroxy-2-chloro-6-(trifluoromethyl)pyridine; 2-Chloro-4-hydroxy-6-(trifluoromethyl)pyridine; 2-Chloro-6-(trifluoromethyl)pyridin-4-ol; 2-Chloro-6-(trifluoromethyl)-4-pyridinol; 4-Pyridinol, 2-chloro-6-(trifluoromethyl)-; 2-Chloro-6-trifluoromethylpyridin-4-ol
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(Trifluoromethyl)Pyridin-4-Ol is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and compliance with your project specifications. Our commitment to consistent quality and supply reliability supports your R&D and production timelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.