Description

3-Bromo-2-Fluoro-6-Methoxypyridine is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials, such as components for OLEDs or conductive polymers, due to its modifiable aromatic core.
• Chemical Biology Probes: Utilized to build molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Bromo-2-Fluoro-6-Methoxypyridine
CAS No.	1227599-27-0
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	2-Fluoro-3-bromo-6-methoxypyridine; 6-Methoxy-3-bromo-2-fluoropyridine; 3-Bromo-2-fluoro-6-methoxypyridine; 2-Fluoro-6-methoxy-3-bromopyridine; Pyridine, 3-bromo-2-fluoro-6-methoxy-; 1227599-27-0
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Fluoro-6-Methoxypyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA), including purity assay and impurity profile by HPLC/GC, is supplied with each shipment to guarantee consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.