Description

4-Bromomethyl-2-Hydroxy-6-(Trifluoromethyl)Pyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive bromomethyl group and a trifluoromethyl substituent, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used to develop advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	4-Bromomethyl-2-Hydroxy-6-(Trifluoromethyl)Pyridine
CAS No.	1227594-55-9
Molecular Formula	C8H5BrF3NO
Molecular Weight	268.03 g/mol
Synonyms	2-Hydroxy-6-(trifluoromethyl)-4-pyridinemethanol, 4-Bromomethyl Ester; 4-(Bromomethyl)-2-hydroxy-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-pyridinol, 4-(bromomethyl)-; 2-Hydroxy-4-bromomethyl-6-trifluoromethylpyridine; 4-Bromo-2-hydroxy-6-(trifluoromethyl)pyridine (common misnomer, verify structure); 2(1H)-Pyridinone, 4-(bromomethyl)-6-(trifluoromethyl)-; Bromomethyl-hydroxy-trifluoromethylpyridine intermediate
EINECS	Contact for details

Quality Control

Our 4-Bromomethyl-2-Hydroxy-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in secondary opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.